ARG63627
anti-DKK2 antibody
anti-DKK2 antibody for Western blot and Human
Developmental Biology antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes DKK2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog |
| Tested Application | WB |
| Specificity | From sequence analysis it is possible that this product will crossreact with DKK4, unfortunately this has not yet been specifically tested. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DKK2 |
| Antigen Species | Human |
| Immunogen | ATYSSKARLHVCQKI |
| Conjugation | Un-conjugated |
| Alternate Names | Dickkopf-related protein 2; hDkk-2; DKK-2; Dickkopf-2; Dkk-2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008] |
| Research Area | Developmental Biology antibody; Signaling Transduction antibody |
| Calculated MW | 28 kDa |
| PTM | May be proteolytically processed by a furin-like protease. |
Images (1) Click the Picture to Zoom In
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ARG63627 anti-DKK2 antibody WB image
Western Blot: Human Heart lysate (35 µg protein in RIPA buffer) stained with ARG63627 anti-DKK2 antibody at 2 µg/ml dilution.
