ARG64114

anti-DISC1 antibody

anti-DISC1 antibody for Western blot and Human

Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes DISC1
Tested Reactivity Hu
Tested Application WB
Specificity This antibody is expected to recognise isoforms L ( NP_061132.2) and Lv (NP_001012975.1) only.
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name DISC1
Antigen Species Human
Immunogen C-HSEDKRKTPLKVLE
Conjugation Un-conjugated
Alternate Names Disrupted in schizophrenia 1 protein; SCZD9; C1orf136

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.1 - 0.3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 27185 Human DISC1

Swiss-port # Q9NRI5 Human Disrupted in schizophrenia 1 protein

Background This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Research Area Neuroscience antibody
Calculated MW 94 kDa

Images (1) Click the Picture to Zoom In

  • ARG64114 anti-DISC1 antibody WB image

    Western Blot: human brain (hippocampus) lysate (35 µg protein in RIPA buffer) stained with ARG64114 anti-DISC1 antibody at 0.1 µg/ml dilution.