ARG65142
anti-DIAPH1 antibody
anti-DIAPH1 antibody for Western blot and Mouse
Signaling Transduction antibody
Overview
Product Description | Goat Polyclonal antibody recognizes DIAPH1 |
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Tested Reactivity | Ms |
Predict Reactivity | Hu |
Tested Application | WB |
Specificity | This antibody is expected to recognize both reported isoforms (NP_005210.3; NP_001073280.1). |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | DIAPH1 |
Antigen Species | Human |
Immunogen | C-QTKTSKAKKDQ |
Conjugation | Un-conjugated |
Alternate Names | DRF1; Diaphanous-related formin-1; LFHL1; DFNA1; Protein diaphanous homolog 1; hDIA1; DIA1 |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Background | This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Research Area | Signaling Transduction antibody |
Calculated MW | 141 kDa |
PTM | Phosphorylation at Thr-768 is stimulated by cAMP and regulates stability, complex formation and mitochondrial movement. |
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