ARG66376

anti-DHX8 antibody

anti-DHX8 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes DHX8
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name DHX8
Antigen Species Human
Immunogen Synthetic peptide within aa. 360-440 of Human DHX8.
Conjugation Un-conjugated
Alternate Names PRP22; RNA helicase HRH1; DEAH box protein 8; PRPF22; ATP-dependent RNA helicase DHX8; EC 3.6.4.13; HRH1; DDX8

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 140 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.5% BSA
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1659 Human DHX8

Swiss-port # Q14562 Human ATP-dependent RNA helicase DHX8

Gene Symbol DHX8
Gene Full Name DEAH (Asp-Glu-Ala-His) box polypeptide 8
Background This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Function Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [UniProt]
Calculated MW 139 kDa

Images (1) Click the Picture to Zoom In

  • ARG66376 anti-DHX8 antibody WB image

    Western blot: HeLa cell lysate stained with ARG66376 anti-DHX8 antibody at 1:500 dilution.