ARG66492

anti-Cytokeratin 4 antibody

anti-Cytokeratin 4 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Mouse Monoclonal antibody recognizes Cytokeratin 4
Tested Reactivity Hu
Tested Application IHC-P
Host Mouse
Clonality Monoclonal
Isotype IgG1, kappa
Target Name Cytokeratin 4
Antigen Species Human
Immunogen Synthetic peptide derived from Human Cytokeratin 4.
Conjugation Un-conjugated
Alternate Names K4; CK4; CK-4; CYK4; WSN1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:500
Application Note IHC-P: Antigen Retrieval: Citric acid buffer (pH 6.0) was used.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.5% BSA
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3851 Human KRT4

Swiss-port # P19013 Human Keratin, type II cytoskeletal 4

Gene Symbol KRT4
Gene Full Name keratin 4
Background The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Calculated MW 57 kDa

Images (1) Click the Picture to Zoom In

  • ARG66492 anti-Cytokeratin 4 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human esophageal squamous carcinoma stained with ARG66492 anti-Cytokeratin 4 antibody at 1:200 (4°C, overnight). Antigen Retrieval: Citric acid buffer (pH 6.0) was used.