ARG45345
anti-Cystatin SA / CST2 antibody [5M60]
anti-Cystatin SA / CST2 antibody [5M60] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody [5M60] recognizes Cystatin SA / CST2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5M60 |
| Isotype | IgG2 |
| Target Name | Cystatin SA / CST2 |
| Antigen Species | Human |
| Immunogen | Recombinant Human Cystatin SA / CST2. |
| Conjugation | Un-conjugated |
| Alternate Names | CST2; Cystatin SA; Cystatin-SA; Cystatin; Salivary Cysteine (Thiol) Protease Inhibitor; Cysteine-Proteinase Inhibitor; Cystatin S5; Cystatin-S5; Cystatin-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G chromatography |
| Buffer | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CST2 |
| Gene Full Name | Cystatin SA |
| Background | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008] |
| Function | Thiol protease inhibitor. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 16 kDa |
| PTM | Disulfide bond. [UniProt] |
