ARG56487
anti-CysLT2 Receptor antibody
anti-CysLT2 Receptor antibody for ELISA,Flow cytometry,Immunohistochemistry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CysLT2 Receptor |
|---|---|
| Tested Reactivity | Hu |
| Species Does Not React With | Ms, Rat, Sheep |
| Tested Application | ELISA, FACS, IHC, WB |
| Specificity | This antibody does not react to CysLT1 receptor. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CysLT2 Receptor |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 330-346 of Human CysLT2 Receptor. (TKCVFPVSVWLRKETRV) |
| Conjugation | Un-conjugated |
| Alternate Names | Cysteinyl leukotriene receptor 2; CYSLT2; GPCR21; CysLTR2; HG57; hGPCR21; HPN321; KPG_011; PSEC0146; CYSLT2R; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4) |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CYSLTR2 |
| Gene Full Name | cysteinyl leukotriene receptor 2 |
| Background | The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008] |
| Function | Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. [UniProt] |
| Calculated MW | 40 kDa |
