ARG63517
anti-Coronin 1 / TACO antibody
anti-Coronin 1 / TACO antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Controls and Markers antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes Coronin 1 / TACO |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Coronin 1 / TACO |
| Antigen Species | Human |
| Immunogen | C-KRLDRLEETVQAK |
| Conjugation | Un-conjugated |
| Alternate Names | Clipin-A; Coronin-1A; Coronin-like protein A; CLABP; IMD8; CLIPINA; Tryptophan aspartate-containing coat protein; HCORO1; Coronin-like protein p57; TACO; p57 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16. [provided by RefSeq, Sep 2010] |
| Research Area | Controls and Markers antibody; Signaling Transduction antibody |
| Calculated MW | 51 kDa |
| PTM | phosphorylation at Thr-412 by PKC strongly down-regulates the association with actin. Polyubiquitinated by RNF128 with 'Lys-48'-linked chains, leading to proteasomal degradation. |
Images (4) Click the Picture to Zoom In
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ARG63517 anti-Coronin 1 / TACO antibody WB image
Western Blot: 1). Mock transfection; 2) CORO1A (RC210753) expressing plasmid transfected HEK293 cell lysate standed with ARG63517 anti-Coronin 1 / TACO antibody
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ARG63517 anti-Coronin 1 / TACO antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human spleen tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63517 anti-Coronin 1 / TACO antibody at 3.75 µg/ml dilution followed by AP-staining.
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ARG63517 anti-Coronin 1 / TACO antibody WB image
Western blot: 35 µg of Human lymphoblastoid lysate (in RIPA buffer) stained with ARG63517 anti-Coronin 1 / TACO antibody at 0.3 µg/ml dilution and incubated at RT for 1 hour.
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ARG63517 anti-Coronin 1 / TACO antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63517 anti-Coronin 1 / TACO antibody at 3.75 µg/ml dilution followed by AP-staining.
