ARG10083
anti-Colorectal carcinoma antibody [Y94]
anti-Colorectal carcinoma antibody [Y94] for IHC-Formalin-fixed paraffin-embedded sections and Human
Controls and Markers antibody; Colorectal Carcinoma Marker antibody
Overview
| Product Description | Mouse Monoclonal antibody [Y94] recognizes Colorectal Carcinoma |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Y94 |
| Isotype | IgG1, kappa |
| Target Name | Colorectal carcinoma |
| Antigen Species | Human |
| Immunogen | Human colorectal carcinoma |
| Conjugation | Un-conjugated |
Application Instructions
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G affinity purified |
| Buffer | 0.01M PBS (pH 7.0) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Background | Colorectal carcinoma is the cancer developed in the colon or rectum of the digestive system. In developed countries, it is the most common cancer in aging population. Genetic deposition and a less active life style contribute to the development of the cancer. Molecular pathological study showed that altered Wnt-APC-β-catenim signalling pathway, mutated p53, and deactivated TGF-β and DCC (Deleted in Colon Cancer) are involved with the pathogenesis. The cancer is currently screened with a fecal occult blood test in people over 50 years old and the malignancy is confirmed by tumour biopsy. The search for specific biomarker for non-invasive test is still ongoing. Tumour associated antigen, TAG-72, is a high molecular weight glycoprotein found at the cell surface in a variety of cancers including gastric cancer, ovarian cancer, colon cancer, breast cancer and pancreatic cancer. It has been used as a tumour marker and therapeutic target for cancer treatment. |
|---|---|
| Highlight | Related Antibody Duos and Panels: ARG30013 Colorectal Carcinoma Marker Antibody Duo (Colorectal carcinoma antibody, PKM2) Related products: Colorectal carcinoma antibodies; Colorectal carcinoma Duos / Panels; Anti-Mouse IgG secondary antibodies; |
| Research Area | Controls and Markers antibody; Colorectal Carcinoma Marker antibody |
