ARG57024
anti-Cathepsin S antibody [1F9]
anti-Cathepsin S antibody [1F9] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1F9] recognizes Cathepsin S |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1F9 |
| Isotype | IgG2b, kappa |
| Target Name | Cathepsin S |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 17-331 of Human Cathepsin S. |
| Conjugation | Un-conjugated |
| Alternate Names | Cathepsin S; EC 3.4.22.27 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CTSS |
| Gene Full Name | cathepsin S |
| Background | The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
| Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. [UniProt] |
| Calculated MW | 37 kDa |
Images (2) Click the Picture to Zoom In
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ARG57024 anti-Cathepsin S antibody [1F9] WB image
Western blot: 20 ng of Recombinant Human 1) CTSB, 2) CTSD, 3) CTSE, 4) CTSF, 5) CTSH, 6) CTSK, 7) CTSL, 8) CTSS, 9) CTSW, and 10) CTSZ stained with ARG57024 anti-Cathepsin S antibody [1F9] at 1:1000.
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ARG57024 anti-Cathepsin S antibody [1F9] WB image
Western blot: 40 µg of 1) HeLa cell lysate, 2) U87MG cell lysate, 3) A549 cell lysate stained with ARG57024 anti-Cathepsin S antibody [1F9] at 1:500.
