ARG64546

anti-Cathepsin K antibody

anti-Cathepsin K antibody for Western blot and Human

Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes Cathepsin K
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog, Pig
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name Cathepsin K
Antigen Species Human
Immunogen C-KTHRKQYNNKVDE
Conjugation Un-conjugated
Alternate Names Cathepsin X; CTS02; CTSO; PYCD; Cathepsin O; PKND; EC 3.4.22.38; Cathepsin K; Cathepsin O2; CTSO1; CTSO2

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1513 Human CTSK

Swiss-port # P43235 Human Cathepsin K

Background The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq, Jul 2008]
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 37 kDa

Images (1) Click the Picture to Zoom In

  • ARG64546 anti-Cathepsin K antibody WB image

    Western Blot: Human Lung lysate (35 µg protein in RIPA buffer) stained with ARG64546 anti-Cathepsin K antibody at 1 µg/ml dilution.