ARG55067

anti-Catalase antibody

anti-Catalase antibody for Western blot and Human,Mouse

Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody; Peroxisome Marker antibody

Overview

Product Description Mouse Monoclonal antibody recognizes Catalase
Tested Reactivity Hu, Ms
Predict Reactivity Bov, Rat, Pig, Zfsh
Tested Application WB
Host Mouse
Clonality Monoclonal
Clone 626CT4.3.8
Isotype IgG2a
Target Name Catalase
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 152-180 (Center) of Human Catalase.
Conjugation Un-conjugated
Alternate Names Catalase; EC 1.11.1.6

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:100 - 1:1600
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control K562

Properties

Form Liquid
Buffer Crude Ascites and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12359 Mouse CAT

GeneID: 847 Human CAT

Swiss-port # P04040 Human Catalase

Swiss-port # P24270 Mouse Catalase

Gene Symbol CAT
Gene Full Name catalase
Background This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
Function Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. [UniProt]
Cellular Localization Peroxisome.
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody; Peroxisome Marker antibody
Calculated MW 60 kDa
PTM The N-terminus is blocked.

Images (1) Click the Picture to Zoom In

  • ARG55067 anti-Catalase antibody WB image

    Western blot: 35 µg of K562 cell lysate stained with ARG55067 anti-Catalase antibody.