ARG54846
anti-Calcipressin 1 antibody
anti-Calcipressin 1 antibody for Western blot and Human
Neuroscience antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Calcipressin 1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Bov, Hm |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Calcipressin 1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 222-252 (C-terminus) of Human Calcipressin 1. |
| Conjugation | Un-conjugated |
| Alternate Names | RCN1; Calcipressin-1; MCIP1; ADAPT78; Down syndrome critical region protein 1; DSCR1; DSC1; Regulator of calcineurin 1; Myocyte-enriched calcineurin-interacting protein 1; CSP1; Adapt78 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Endothelial |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RCAN1 |
| Gene Full Name | regulator of calcineurin 1 |
| Background | The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] |
| Function | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. [UniProt] |
| Research Area | Neuroscience antibody |
| Calculated MW | 28 kDa |
Images (1) Click the Picture to Zoom In
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ARG54846 anti-Calcipressin 1 antibody WB image
Western blot: Endothelial tissue lysate stained with ARG54846 anti-Calcipressin 1 antibody.
