ARG55080
anti-Cadherin 20 antibody
anti-Cadherin 20 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Cadherin 20 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Cadherin 20 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 111-140 (N-terminus) of Human Cadherin 20. |
| Conjugation | Un-conjugated |
| Alternate Names | CDH7L3; Cadherin-20; Cdh7 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HepG2 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CDH20 |
| Gene Full Name | cadherin 20, type 2 |
| Background | This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008] |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 89 kDa |
Images (3) Click the Picture to Zoom In
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ARG55080 anti-Cadherin 20 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded brain tissue stained with ARG55080 anti-Cadherin 20 antibody.
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ARG55080 anti-Cadherin 20 antibody WB image
Western blot: 35 µg of HepG2 cell lysate stained with ARG55080 anti-Cadherin 20 antibody.
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ARG55080 anti-Cadherin 20 antibody FACS image
Flow Cytometry: HepG2 cells stained with ARG55080 anti-Cadherin 20 antibody (bottom histogram) or without primary antibody control (top histogram), followed by incubation with FITC labelled secondary antibody.
