ARG67064
anti-Cadherin 17 antibody [SQab30334]
anti-Cadherin 17 antibody [SQab30334] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab30334] recognizes Cadherin 17 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30334 |
| Target Name | Cadherin 17 |
| Antigen Species | Human |
| Immunogen | Recombinant protein fragment of Cadherin 17 |
| Conjugation | Un-conjugated |
| Protein Full Name | Cadherin 17 |
| Alternate Names | CDH17; Cadherin 17; HPT-1; Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; LI Cadherin (Liver-Intestine); Liver-Intestine Cadherin; Cadherin-17; Cadherin; Human Intestinal Peptide-Associated Transporter HPT-1; Human Peptide Transporter 1; HPT-1 Cadherin; LI Cadherin; Cadherin-16; LI-Cadherin; CDH16; HPT1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | -20°C |
| Note | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CDH17 |
| Gene Full Name | cadherin 17 |
| Background | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. [UniProt] |
| Cellular Localization | Cell membrane, Membrane. [UniProt] |
| Calculated MW | 92 kDa |
| PTM | Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG67064 anti-Cadherin 17 antibody [SQab30334] IHC-P image
Immunohistochemistry: Human colon tissue stained with ARG67064 anti-Cadherin 17 antibody [SQab30334] at 1:100 dilution.
