ARG45343

anti-CXCL13 / BCA1 antibody [19N1]

anti-CXCL13 / BCA1 antibody [19N1] for IHC-Formalin-fixed paraffin-embedded sections and Mouse

Overview

Product Description Rat Monoclonal antibody [19N1] recognizes CXCL13 / BCA1
Tested Reactivity Ms
Tested Application IHC-P
Host Rat
Clonality Monoclonal
Clone 19N1
Isotype IgG2
Target Name CXCL13 / BCA1
Antigen Species Mouse
Immunogen Recombinant Mouse CXCL13 / BCA1.
Conjugation Un-conjugated
Alternate Names BCA-1; Angie; C-X-C motif chemokine 13; CXC chemokine BLC; ANGIE2; B lymphocyte chemoattractant; B cell-attracting chemokine 1; BLR1L; Small-inducible cytokine B13; SCYB13; ANGIE; BLC; BCA1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:200
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Powder
Purification Protein G/A chromatography
Buffer PBS
Reconstitution PBS
Concentration 0.2 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 55985 Mouse CXCL13

Swiss-port # O55038 Mouse C-X-C motif chemokine 13

Gene Symbol CXCL13
Gene Full Name C-X-C Motif Chemokine Ligand 13
Background B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Oct 2014]
Function Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 12 kDa
PTM Disulfide bond. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG45343 anti-CXCL13 / BCA1 antibody [19N1] IHC-P image

    Immunohistochemistry: Mouse kidney stained with ARG45343 anti-CXCL13 / BCA1 antibody [19N1].