ARG45343
anti-CXCL13 / BCA1 antibody [19N1]
anti-CXCL13 / BCA1 antibody [19N1] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody [19N1] recognizes CXCL13 / BCA1 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 19N1 |
| Isotype | IgG2 |
| Target Name | CXCL13 / BCA1 |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse CXCL13 / BCA1. |
| Conjugation | Un-conjugated |
| Alternate Names | BCA-1; Angie; C-X-C motif chemokine 13; CXC chemokine BLC; ANGIE2; B lymphocyte chemoattractant; B cell-attracting chemokine 1; BLR1L; Small-inducible cytokine B13; SCYB13; ANGIE; BLC; BCA1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G/A chromatography |
| Buffer | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CXCL13 |
| Gene Full Name | C-X-C Motif Chemokine Ligand 13 |
| Background | B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Oct 2014] |
| Function | Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 12 kDa |
| PTM | Disulfide bond. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG45343 anti-CXCL13 / BCA1 antibody [19N1] IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45343 anti-CXCL13 / BCA1 antibody [19N1].
