ARG63466
anti-CREB3L4 / AIBZIP antibody
anti-CREB3L4 / AIBZIP antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes CREB3L4 / AIBZIP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CREB3L4 / AIBZIP |
| Antigen Species | Human |
| Immunogen | C-PSGRIRSVLHADEM |
| Conjugation | Un-conjugated |
| Alternate Names | Transcript induced in spermiogenesis protein 40; cAMP-responsive element-binding protein 3-like protein 4; Androgen-induced basic leucine zipper protein; Cyclic AMP-responsive element-binding protein 3-like protein 4; cAMP-responsive element-binding protein 4; CREB4; CREB3; hJAL; Tisp40; ATCE1; JAL; Cyclic AMP-responsive element-binding protein 4; Attaching to CRE-like 1; CREB-4; AIbZIP; AIBZIP |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8TEY5 Human Cyclic AMP-responsive element-binding protein 3-like protein 4 |
|---|---|
| Background | This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| Research Area | Gene Regulation antibody |
| Calculated MW | 43 kDa |
| PTM | N-glycosylated in the C-terminal region. Controlled by regulated intramembrane proteolysis (RIP). Following ER stress a fragment containing the cytoplasmic transcription factor domain is released by proteolysis. The cleavage seems to be performed sequentially by site-1 and site-2 proteases (PS1 and PS2). PS1 cleavage may be suppressed by a determinant in the C-terminal region (By similarity). |
Images (2) Click the Picture to Zoom In
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ARG63466 anti-CREB3L4 / AIBZIP antibody WB image
Western blot: Human Placenta lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63466 anti-CREB3L4 / AIBZIP antibody at 0.5 µg/ml dilution.
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ARG63466 anti-CREB3L4 / AIBZIP antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Prostate. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63466 anti-CREB3L4 / AIBZIP antibody at 2.5 µg/ml dilution followed by AP-staining.
