ARG45518
anti-CPSF6 antibody [3F11E1]
anti-CPSF6 antibody [3F11E1] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
Overview
| Product Description | Mouse Monoclonal antibody [3F11E1] recognizes CPSF6 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 3F11E1 |
| Isotype | IgG1 |
| Target Name | CPSF6 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human CPSF6. |
| Conjugation | Un-conjugated |
| Alternate Names | CPSF6; Cleavage And Polyadenylation Specific Factor 6; CFIM68; Cleavage Factor Im Complex 68 KDa Subunit; HPBRII-4; HPBRII-7; CFIM72; CFIM; Cleavage And Polyadenylation Specificity Factor 68 KDa Subunit; Cleavage And Polyadenylation Specificity Factor Subunit 6; Cleavage And Polyadenylation Specific Factor 6, 68kDa; Pre-MRNA Cleavage Factor Im 68 KDa Subunit; CPSF 68 KDa Subunit; Protein HPBRII-4/7; Cleavage And Polyadenylation Specific Factor 6, 68kD Subunit; Pre-MRNA Cleavage Factor I, 68kD Subunit; Pre-MRNA Cleavage Factor Im (68kD); CFIm68 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 68 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q16630 Human Cleavage and polyadenylation specificity factor subunit 6 Swiss-port # Q6NVF9 Mouse Cleavage and polyadenylation specificity factor subunit 6 |
|---|---|
| Gene Symbol | CPSF6 |
| Gene Full Name | Cleavage And Polyadenylation Specific Factor 6 |
| Background | The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008] |
| Function | Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNA. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 59 kDa |
| PTM | Methylation; Phosphoprotein. [UniProt] |
Images (9) Click the Picture to Zoom In
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ARG45518 anti-CPSF6 antibody [3F11E1] IHC-P image
Immunohistochemistry: Human squamous cell carcinoma stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 2 μg/ml dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] ICC/IF image
Immunofluorescence: U20S stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 5 μg/ml dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] WB image
Western blot: Hela stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 0.5 μg/ml dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] WB image
Western blot: COS-7 stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 0.5 μg/ml dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] FACS image
Flow Cytometry: HepG2 stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 1 µg/10^6 cells dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] IHC-P image
Immunohistochemistry: Rat brain stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 2 μg/ml dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] WB image
Western blot: Rat brain stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 0.5 μg/ml dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 2 μg/ml dilution.
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ARG45518 anti-CPSF6 antibody [3F11E1] WB image
Western blot: Mouse brain stained with ARG45518 anti-CPSF6 antibody [3F11E1] at 0.5 μg/ml dilution.
