ARG57069
anti-CPOX antibody [36B10]
anti-CPOX antibody [36B10] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [36B10] recognizes CPOX |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 36B10 |
| Isotype | IgG1, kappa |
| Target Name | CPOX |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 111-454 of Human CPOX. |
| Conjugation | Un-conjugated |
| Alternate Names | HCP; CPO; COX; Coproporphyrinogenase; Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial; CPX; Coprogen oxidase; EC 1.3.3.3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P36551 Human Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial |
|---|---|
| Gene Symbol | CPOX |
| Gene Full Name | coproporphyrinogen oxidase |
| Background | The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009] |
| Function | Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. [UniProt] |
| Calculated MW | 50 kDa |
Images (1) Click the Picture to Zoom In
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ARG57069 anti-CPOX antibody [36B10] WB image
Western blot: 40 µg of 1) Recombinant protein CPOX, 2) 293T cell lysate, 3) HepG2 cell lysate, 4) A549 cell lysate, 5) Jurkat cell lysate, 6) K562 cell lysate, 7) LnCaP cell lysate stained with ARG57069 anti-CPOX antibody [36B10] at 1:500.
