ARG54963
anti-COX6A2 antibody
anti-COX6A2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes COX6A2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | COX6A2 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 37-66 (Center) of Human COX6A2. |
| Conjugation | Un-conjugated |
| Alternate Names | COX6AH; Cytochrome c oxidase subunit VIA-muscle; Cytochrome c oxidase polypeptide VIa-heart; Cytochrome c oxidase subunit 6A2, mitochondrial; COX VIa-M; COXVIAH |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Human skeletal muscle |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q02221 Human Cytochrome c oxidase subunit 6A2, mitochondrial |
|---|---|
| Gene Symbol | COX6A2 |
| Gene Full Name | cytochrome c oxidase subunit VIa polypeptide 2 |
| Background | Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq, Jul 2008] |
| Function | This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. [UniProt] |
| Cellular Localization | Mitochondrion inner membrane. |
| Research Area | Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 11 kDa |
Images (2) Click the Picture to Zoom In
-
ARG54963 anti-COX6A2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human skeletal muscle tissue stained with ARG54963 anti-COX6A2 antibody at 1:25 dilution.
-
ARG54963 anti-COX6A2 antibody WB image
Western blot: 20 µg of Human skeletal muscle lysate stained with ARG54963 anti-COX6A2 antibody at 1:1000 dilution.
