ARG64080

anti-CNTFR antibody

anti-CNTFR antibody for Western blot and Mouse

Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes CNTFR
Tested Reactivity Ms
Predict Reactivity Hu, Rat, Dog
Tested Application WB
Specificity This antibody is expected to recognise both reported isoforms (NP_671693.1; NP_001833.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CNTFR
Antigen Species Human
Immunogen CRSNTYPKGFY
Conjugation Un-conjugated
Alternate Names Ciliary neurotrophic factor receptor subunit alpha; CNTFR-alpha; CNTF receptor subunit alpha

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12804 Mouse CNTFR

Swiss-port # O88507 Mouse Ciliary neurotrophic factor receptor subunit alpha

Background This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 41 kDa

Images (1) Click the Picture to Zoom In

  • ARG64080 anti-CNTFR antibody WB image

    Western Blot: mouse brain lysate (35 µg protein in RIPA buffer) stained with ARG64080 anti-CNTFR antibody at 0.3 µg/ml dilution.