ARG11117
anti-CNPase antibody
anti-CNPase antibody for IHC-Frozen sections,Western blot and Human,Mouse,Rat,Cow,Pig
Overview
| Product Description | Goat Polyclonal antibody recognizes CNPase |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Cow, Pig |
| Tested Application | IHC-Fr, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CNPase |
| Antigen Species | Human |
| Immunogen | Recombinant full-length Human CNPase. |
| Conjugation | Un-conjugated |
| Alternate Names | CNPase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP1; CNP; EC 3.1.4.37 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | ~ 48 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 5 mM Sodium azide and 50% Glycerol. |
| Preservative | 5 mM Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CNP |
| Gene Full Name | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| Function | May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. [UniProt] |
| Cellular Localization | Membrane; Lipid-anchor. Melanosome. Note=Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. [UniProt] |
| Calculated MW | 48 kDa |
Images (2) Click the Picture to Zoom In
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ARG11117 anti-CNPase antibody IHC-Fr image
Immunohistochemistry: Frozen section of Mouse striatum stained with ARG11117 anti-CNPase antibody (green) at 1:3000 dilution, and co-stained with ARG10732 anti-Neurofilament NF-L antibody antibody (red) at 1:5000 dilution. Hoechst (blue) for nuclear staining. (Sample preparation: Following transcardial perfusion of mouse with 4% paraformaldehyde, the brain was post fixed for 24 hours, cut to 45 µM, and free-floating sections were stained with above antibodies.).
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ARG11117 anti-CNPase antibody WB image
Western blot: Rat brain, Rat spinal cord, Mouse brain, Mouse spinal cord, Cow spinal cord and Pig spinal cord lysates stained with ARG11117 anti-CNPase antibody at 1:5000 dilution.
Bands at 46 kDa and 48 kDa mark correspond to the two major isotypes.
