ARG59941
anti-CMPK1 antibody
anti-CMPK1 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CMPK1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CMPK1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 69-228 of Human CMPK1 (NP_057392.1). |
| Conjugation | Un-conjugated |
| Alternate Names | CK; UMP/CMP kinase; CMK; EC 2.7.4.14; Nucleoside-diphosphate kinase; Uridine monophosphate/cytidine monophosphate kinase; UMP/CMPK; UMP-CMP kinase; dCMP kinase; Deoxycytidylate kinase; EC 2.7.4.6; CMPK; UMP-CMPK; UMPK; UMK |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HL-60 | ||||||||
| Observed Size | 22 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CMPK1 |
| Gene Full Name | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic |
| Background | This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012] |
| Function | Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. Note=Predominantly cytoplasmic, less than 15% nuclear. [UniProt] |
| Calculated MW | 22 kDa |
Images (2) Click the Picture to Zoom In
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ARG59941 anti-CMPK1 antibody ICC/IF image
Immunofluorescence: MCF7 cells stained with ARG59941 anti-CMPK1 antibody.
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ARG59941 anti-CMPK1 antibody WB image
Western blot: 25 µg of HL-60 cell lysate stained with ARG59941 anti-CMPK1 antibody at 1:1000 dilution.
