ARG59262
anti-CLPX antibody
anti-CLPX antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CLPX |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CLPX |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 449-477 (C-terminus) of Human CLPX. |
| Conjugation | Un-conjugated |
| Alternate Names | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Human heart | ||||||||
| Observed Size | 70 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O76031 Human ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial |
|---|---|
| Gene Symbol | CLPX |
| Gene Full Name | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| Function | ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradation by the Clp complex. Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure. [UniProt] |
| Cellular Localization | Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. [UniProt] |
| Calculated MW | 69 kDa |
Images (3) Click the Picture to Zoom In
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ARG59262 anti-CLPX antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatocarcinoma stained with ARG59262 anti-CLPX antibody.
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ARG59262 anti-CLPX antibody WB image
Western blot: 35 µg of Human heart lysate stained with ARG59262 anti-CLPX antibody at 1:1000 dilution.
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ARG59262 anti-CLPX antibody FACS image
Flow Cytometry: 293 cells stained with ARG59262 anti-CLPX antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
