ARG63785
anti-CLCA1 antibody
anti-CLCA1 antibody for Western blot and Human
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes CLCA1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | No cross-reactivity expected with CLCA2 and 3. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CLCA1 |
| Antigen Species | Human |
| Immunogen | C-TVTSKTNKDTSK |
| Conjugation | Un-conjugated |
| Alternate Names | hCLCA1; CACC1; Calcium-activated chloride channel regulator 1; Calcium-activated chloride channel family member 1; CaCC-1; Calcium-activated chloride channel protein 1; EC 3.4.-.-; GOB5; CACC; CLCRG1; hCaCC-1 |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # A8K7I4 Human Calcium-activated chloride channel regulator 1 |
|---|---|
| Background | This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 100 kDa |
| PTM | Glycosylated. The 125-kDa product is autoproteolytically processed by the metalloprotease domain and yields to two cell-surface-associated subunits, a 90-kDa protein and a group of 37-to 41-kDa proteins. The cleavage is necessary for calcium-activated chloride channel (CaCC) activation activity. |
Images (1) Click the Picture to Zoom In
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ARG63785 anti-CLCA1 antibody WB image
Western Blot: Human Duodenum lysate (35 µg protein in RIPA buffer) stained with ARG63785 anti-CLCA1 antibody at 1 µg/ml dilution.
