Overview

Product Description	Rabbit Polyclonal antibody recognizes CKAP4
Tested Reactivity	Hu, Ms, Rat
Tested Application	ICC/IF, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	CKAP4
Antigen Species	Human
Immunogen	Synthetic peptide of Human CKAP4
Conjugation	Un-conjugated
Alternate Names	ERGIC-63; p63; CLIMP-63; Climp-63; 63-kDa cytoskeleton-linking membrane protein; Cytoskeleton-associated protein 4

Application Instructions

Application Suggestion	Tested Application Dilution ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	HepG2

Properties

Form	Liquid
Purification	Affinity purification with immunogen.
Buffer	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 10970 Human CKAP4 GeneID: 216197 Mouse CKAP4 Swiss-port # Q07065 Human Cytoskeleton-associated protein 4 Swiss-port # Q8BMK4 Mouse Cytoskeleton-associated protein 4
Gene Symbol	CKAP4
Gene Full Name	cytoskeleton-associated protein 4
Function	High-affinity epithelial cell surface receptor for APF. Mediates the anchoring of the endoplasmic reticulum to microtubules. [UniProt]
Calculated MW	66 kDa
PTM	Reversibly palmitoylated. Palmitoylation at Cys-100 by DHHC2 is required for its trafficking from the ER to the plasma membrane and for its perinuclear localization. Increased phosphorylation during mitosis prevents binding to microtubules.

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