ARG57084
anti-CINP antibody [1G10]
anti-CINP antibody [1G10] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1G10] recognizes CINP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1G10 |
| Isotype | IgG1, kappa |
| Target Name | CINP |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-212 of Human CINP. |
| Conjugation | Un-conjugated |
| Alternate Names | CDK2-interacting protein; Cyclin-dependent kinase 2-interacting protein |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9BW66 Human Cyclin-dependent kinase 2-interacting protein |
|---|---|
| Gene Symbol | CINP |
| Gene Full Name | cyclin-dependent kinase 2 interacting protein |
| Background | The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. [provided by RefSeq, Jul 2013] |
| Function | Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling. [UniProt] |
| Calculated MW | 24 kDa |
| PTM | Phosphorylated by CDC7 but not by CDK2. |
Images (1) Click the Picture to Zoom In
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ARG57084 anti-CINP antibody [1G10] WB image
Western blot: 40 µg of 1) Jurkat cell lysate, 2) K562 cell lysate, 3) 293T cell lysate, 4) HepG2 cell lysate, 5) A549 cell lysate, 6) MCF7 cell lysate, 7) LnCap cell lysate, 8) HeLa cell lysate, 9) SK-OV-3 cell lysate stained with ARG57084 anti-CINP antibody [1G10] at 1:1000.
