ARG44799

anti-CHCHD6 antibody

anti-CHCHD6 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Mouse Monoclonal antibody recognizes CHCHD6
Tested Reactivity Hu, Ms
Tested Application IHC-P, WB
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name CHCHD6
Antigen Species Human
Epitope RVSFGVDEEE RVRVLQGVRL SENVVNRMKE PSSPPPAPTS STFGLQDGNL RAPHKESTLP RSGSSGGQQP SGMKEGVKRY EQEHAAIQDK LFQVAKRERE AATKHSKASL PTGEGSISHE EQKSVRLARE LESREAELRR RDTFYKEQLE RIERKNAEMY KLSSEQFHEA ASKMESTIKP
Conjugation Un-conjugated
Alternate Names CHCHD6 ; Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6; CHCM1; PPP1R23; MICOS25; Mic25; Mitochondrial Contact Site And Cristae Organizing System Subunit 25; Coiled-Coil-Helix Cristae Morphology Protein 1; Protein Phosphatase 1, Regulatory Subunit 23; MICOS Complex Subunit MIC25; MGC13016; Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 6, Mitochondrial; Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 6; Coiled-Coil-Helix Cristae Morphology 1; Coiled Coil Helix Cristae Morphology 1; MIC25

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:200
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purification
Buffer PBS with 0.09% sodium azide
Preservative 0.09% sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 66098 Mouse CHCHD6

GeneID: 84303 Human CHCHD6

Swiss-port # Q91VN4 Mouse MICOS complex subunit Mic25

Swiss-port # Q9BRQ6 Human MICOS complex subunit MIC25

Gene Symbol CHCHD6
Gene Full Name Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6
Background Involved in cellular response to DNA damage stimulus and cristae formation. Located in cytosol and mitochondrial inner membrane. Part of MICOS complex. [provided by Alliance of Genome Resources, Apr 2022]
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. [Uniprot]
Cellular Localization Membrane, Mitochondrion, Mitochondrion inner membrane. [Uniprot]
PTM Disulfide bond, Lipoprotein, Myristate, Phosphoprotein. [Uniprot]

Images (2) Click the Picture to Zoom In

  • ARG44799 anti-CHCHD6 antibody IHC-P image

    Immunohistochemistry: Human stomach stained with ARG44799 anti-CHCHD6 antibody at 7.5 µg/mL dilution.

  • ARG44799 anti-CHCHD6 antibody WB image

    Western blot: Jurkat and NIH/3T3 stained with ARG44799 anti-CHCHD6 antibody at 1 µg/mL dilution.