ARG67241

anti-CDX2 antibody

anti-CDX2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CDX2
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CDX2
Conjugation Un-conjugated
Alternate Names CDX2; Caudal Type Homeobox 2; CDX3; Caudal-Type Homeobox Protein 2; Homeobox Protein CDX-2; CDX-3; Caudal Type Homeo Box Transcription Factor 2; Caudal Type Homeobox Transcription Factor 2; Homeobox Protein MiniCDX2; CDX2/AS

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:500
WB1:1000 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified
Buffer 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol.
Preservative 0.025% ProClin 300
Stabilizer 20% Glycerol
Concentration 1.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1045 Human CDX2

GeneID: 12591 Mouse CDX2

Swiss-port # P43241 Mouse Homeobox protein CDX-2

Swiss-port # Q99626 Human Homeobox protein CDX-2

Gene Symbol CDX2
Gene Full Name Caudal Type Homeobox 2
Background This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]
Function Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA. [Uniprot]
Cellular Localization Nucleus. [Uniprot]
Calculated MW 34 kDa
PTM Phosphoprotein, Ubl conjugation. [Uniprot]

Images (5) Click the Picture to Zoom In

  • ARG67241 anti-CDX2 antibody IHC-P image

    Immunohistochemistry: Human Colorectal adenocarcinoma stained with ARG67241 anti-CDX2 antibody at 1:100 dilution.

  • ARG67241 anti-CDX2 antibody WB image

    Western blot: Caco-2 stained with ARG67241 anti-CDX2 antibody at 1:1000 dilution.

  • ARG67241 anti-CDX2 antibody WB image

    Western blot: Rat colon stained with ARG67241 anti-CDX2 antibody at 1:1000 dilution.

  • ARG67241 anti-CDX2 antibody WB image

    Western blot: Mouse colon stained with ARG67241 anti-CDX2 antibody at 1:1000 dilution.

  • ARG67241 anti-CDX2 antibody IHC-P image

    Immunohistochemistry: Human Colorectal adenocarcinoma stained with ARG67241 anti-CDX2 antibody at 1:100 dilution.