ARG63940
anti-CDX2 antibody
anti-CDX2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes CDX2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Dog |
| Tested Application | IHC-P, WB |
| Specificity | No cross-reactivity expected with CDX1 and 4 |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CDX2 |
| Antigen Species | Human |
| Immunogen | EQLSPGGQRRNLCE |
| Conjugation | Un-conjugated |
| Alternate Names | CDX2/AS; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012] |
| Research Area | Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody |
| Calculated MW | 34 kDa |
| PTM | Phosphorylation of Ser-60 mediates the transactivation capacity. |
Images (3) Click the Picture to Zoom In
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ARG63940 anti-CDX2 antibody WB image
Western Blot: Human Kidney lysate (35 µg protein in RIPA buffer) stained with ARG63940 anti-CDX2 antibody at 1 µg/ml dilution.
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ARG63940 anti-CDX2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63940 anti-CDX2 antibody at 5 µg/ml dilution followed by AP-staining.
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ARG63940 anti-CDX2 antibody WB image
Western blot: 35 µg of Human colon lysate (in RIPA buffer) stained with ARG63940 anti-CDX2 antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
