ARG62429
anti-CD90.2 / Thy 1.2 antibody [IBL-1]
anti-CD90.2 / Thy 1.2 antibody [IBL-1] for Flow cytometry,ICC/IF,IHC-Frozen sections and Mouse
Developmental Biology antibody; Immune System antibody; Neuroscience antibody
Overview
| Product Description | Rat Monoclonal antibody [IBL-1] recognizes CD90.2 / Thy 1.2 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS, ICC/IF, IHC-Fr |
| Specificity | The clone IBL-1 recognizes the mouse Thy1.2 alloantigen, also known as CD90.2, which is expressed by thymocytes and peripheral T lymphocytes. Clone IBL-1 reacts with Thy1.2 mice such as BALB/C, but not with Thy1.1 mice eg. AKR. |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | IBL-1 |
| Isotype | IgG2b |
| Target Name | CD90.2 / Thy 1.2 |
| Antigen Species | Mouse |
| Immunogen | Mouse EL-4 T cell lymphoma cells. |
| Conjugation | Un-conjugated |
| Alternate Names | Thy-1 membrane glycoprotein; Thy-1 antigen; CD antigen CD90; CDw90; CD90 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Mouse thymus. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified Antibody |
| Buffer | 1X PBS and 0.1% Sodium azide |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Thy1 |
| Gene Full Name | thymus cell antigen 1, theta |
| Background | This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
| Function | May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [UniProt] |
| Research Area | Developmental Biology antibody; Immune System antibody; Neuroscience antibody |
| Calculated MW | 18 kDa |
Clone References
Immunohistological localization of endogenous unlabeled stem cells in wounded skin.
Impaired cutaneous immune responses in Thy-1-deficient mice.
Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases.
Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin.
Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes.
