ARG65399
anti-CD90 / Thy 1 antibody [5E10] (azide free)
anti-CD90 / Thy 1 antibody [5E10] (azide free) for CyTOF®-candidate,Flow cytometry,ICC/IF,IHC-Frozen sections,Immunoprecipitation,Western blot and Human,Dog,Primates,Pig
Developmental Biology antibody; Immune System antibody; Neuroscience antibody
Overview
| Product Description | Azide free Mouse Monoclonal antibody [5E10] recognizes CD90 / Thy 1 |
|---|---|
| Tested Reactivity | Hu, Dog, NHuPrm, Pig |
| Tested Application | CyTOF®-candidate, FACS, ICC/IF, IHC-Fr, IP, WB |
| Specificity | The clone 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5E10 |
| Isotype | IgG1 |
| Target Name | CD90 / Thy 1 |
| Immunogen | HEL erythroleukemia cells. |
| Conjugation | Un-conjugated |
| Alternate Names | Thy-1 membrane glycoprotein; Thy-1 antigen; CD antigen CD90; CDw90; CD90 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Purification Note | Preserved by filter sterilization. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | THY1 |
| Gene Full Name | Thy-1 cell surface antigen |
| Background | CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions. |
| Function | May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [UniProt] |
| Highlight | Related products: CD90 antibodies; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies |
| Research Area | Developmental Biology antibody; Immune System antibody; Neuroscience antibody |
| Calculated MW | 18 kDa |
Clone References
Amniotic fluid-derived mesenchymal stem cells prevent fibrosis and preserve renal function in a preclinical porcine model of kidney transplantation.
Immunopathogenic role of TH1 cells in autoimmune diabetes: evidence from a T1 and T2 doubly transgenic non-obese diabetic mouse model.
Expression of Thy-1 on human hematopoietic progenitor cells.
Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.
