ARG67240
anti-CD81 antibody
anti-CD81 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD81 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD81 |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | CD81; CD81 Molecule; TSPAN28; Tetraspanin-28; TAPA1; S5.7; CD81 Antigen (Target Of Antiproliferative Antibody 1); 26 KDa Cell Surface Protein TAPA-1; CD81 Antigen; Tspan-28; TAPA-1; Target Of The Antiproliferative Antibody 1; CVID6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| Preservative | 0.025% ProClin 300 |
| Stabilizer | 20% Glycerol |
| Concentration | 1.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CD81 |
| Gene Full Name | CD81 Molecule |
| Background | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
| Function | Also involved in cell adhesion and motility. Positively regulates integrin-mediated adhesion of macrophages, particularly relevant for the inflammatory response in the lung. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane. [Uniprot] |
| Calculated MW | 26 kDa |
| PTM | Disulfide bond. [Uniprot] |
Images (3) Click the Picture to Zoom In
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ARG67240 anti-CD81 antibody IHC-P image
Immunohistochemistry: Human Gastric carcinoma stained with ARG67240 anti-CD81 antibody at 1:100 dilution.
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ARG67240 anti-CD81 antibody ICC/IF image
Immunofluorescence: CE81T stained with ARG67240 anti-CD81 antibody at 1:400 dilution.
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ARG67240 anti-CD81 antibody WB image
Western blot: CE81T stained with ARG67240 anti-CD81 antibody at 1:1000 dilution.
