ARG44027
anti-CD80 antibody
anti-CD80 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD80 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD80 |
| Antigen Species | Human |
| Immunogen | Human CD80 recombinantprotein |
| Conjugation | Un-conjugated |
| Protein Full Name | T-lymphocyte activation antigen CD80 |
| Alternate Names | CD80; CD80 Molecule; CD28LG1; CD28LG; B7.1; B7-1; CD80 Antigen (CD28 Antigen Ligand 1; B7-1 Antigen); T-Lymphocyte Activation Antigen CD80; B-Lymphocyte Activation Antigen B7; CTLA-4 Counter-Receptor B7.1; Activation B7-1 Antigen; LAB7; BB1; B7; Costimulatory Molecule Variant IgV-CD80; Costimulatory Factor CD80; CD80 Molecule; CD80 Antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS containing 0.02% sodium azide |
| Preservative | 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # P33681 Human T-lymphocyte activation antigen CD80 Swiss-port # Q00609 Mouse T-lymphocyte activation antigen CD80 |
|---|---|
| Gene Symbol | CD80 |
| Gene Full Name | CD80 Molecule |
| Background | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. |
| Function | Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. |
| Cellular Localization | Membrane |
| Calculated MW | 33 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein |
Images (3) Click the Picture to Zoom In
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ARG44027 anti-CD80 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44027 anti-CD80 antibody at 5 μg/ml dilution.
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ARG44027 anti-CD80 antibody WB image
Western blot: EL4 stained with ARG44027 anti-CD80 antibody at 1 μg/ml dilution.
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ARG44027 anti-CD80 antibody IHC-P image
Immunofluorescence: Human tonsil stained with ARG44027 anti-CD80 antibody at 20 μg/ml dilution.
