ARG20949
anti-CD72 antibody [10.1.D2] (Biotin)
anti-CD72 antibody [10.1.D2] (Biotin) for Blocking,Cellular activation ,Flow cytometry and Mouse
Overview
| Product Description | Biotin-conjugated Mouse Monoclonal antibody [10.1.D2] recognizes CD72 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | BL, Cell-Act , FACS |
| Specificity | Mouse CD72.1. The clone 10.1.D2 blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 10.1.D2 |
| Isotype | IgG2b, kappa |
| Target Name | CD72 |
| Antigen Species | Mouse |
| Immunogen | DBA/2 mouse spleen cells |
| Conjugation | Biotin |
| Alternate Names | CD antigen CD72; LYB2; B-cell differentiation antigen CD72; Lyb-2; CD72b |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 0.1% Sodium azide. |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.5 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P21855 Mouse B-cell differentiation antigen CD72 |
|---|---|
| Gene Symbol | CD72 |
| Gene Full Name | CD72 antigen |
| Function | Plays a role in B-cell proliferation and differentiation. [UniProt] |
| Calculated MW | 40 kDa |
| PTM | Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity). |
Images (1) Click the Picture to Zoom In
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ARG20949 anti-CD72 antibody [10.1.D2] (Biotin) FACS image
Flow Cytometry: DBA/2 Mouse splenocytes stained with ARG20949 anti-CD72 antibody [10.1.D2] (Biotin) and ARG20852 anti-CD19 antibody [6D5] (PE) followed by Streptavidin (FITC).
