ARG62916
anti-CD69 antibody [FN50]
anti-CD69 antibody [FN50] for CyTOF®-candidate,Flow cytometry,Functional study,IHC-Frozen sections and Human
Developmental Biology antibody; Immune System antibody
Overview
Product Description | Mouse Monoclonal antibody [FN50] recognizes CD69 |
---|---|
Tested Reactivity | Hu |
Tested Application | CyTOF®-candidate, FACS, FuncSt, IHC-Fr |
Specificity | The clone FN50 recognizes CD69, an lymphocyte early activation marker. HLDA IV; WS Code A 91 |
Host | Mouse |
Clonality | Monoclonal |
Clone | FN50 |
Isotype | IgG1 |
Target Name | CD69 |
Antigen Species | Human |
Immunogen | anti-µ-stimulated human B lymphocytes |
Conjugation | Un-conjugated |
Alternate Names | GP32/28; Activation inducer molecule; MLR-3; BL-AC/P26; Leukocyte surface antigen Leu-23; AIM; Early activation antigen CD69; Early T-cell activation antigen p60; EA1; CD antigen CD69; CLEC2C; C-type lectin domain family 2 member C |
Application Instructions
Application Suggestion |
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Application Note | Functional studies: When stimulating peripheral blood T cells, clone FN50 together with TPA synergistically increases cell volume and RNA/DNA synthesis. Addition of FN50 to stimulated peripheral blood B cells has similar, but weaker effect. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
---|---|
Purification | Purified from cell culture supernatant by protein-A affinity chromatography. |
Purity | > 95% (by SDS-PAGE) |
Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
Preservative | 15 mM Sodium azide |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
---|---|
Gene Symbol | CD69 |
Gene Full Name | CD69 molecule |
Background | CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy. |
Function | Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. [UniProt] |
Highlight | Related products: CD69 antibodies; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies |
Research Area | Developmental Biology antibody; Immune System antibody |
Calculated MW | 23 kDa |
PTM | Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes. |
Images (1) Click the Picture to Zoom In