ARG43816
anti-CD62P / P-Selectin antibody
anti-CD62P / P-Selectin antibody for ELISA,Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD62P / P-Selectin. |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | ELISA, FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD62P / P-Selectin |
| Immunogen | Recombinant protein around aa. 40-270 of mouse CD62P. |
| Conjugation | Un-conjugated |
| Protein Full Name | P-selectin |
| Alternate Names | SELP; Selectin P; PADGEM; GMP140; CD62P; CD62; PSEL; GRMP; Platelet Activation Dependent Granule-External Membrane Protein; Selectin P Granule Membrane Protein 140kDa; Antigen CD62; Leukocyte Endothelial Cell Adhesion Molecule 3; CD62 Antigen Like Family Member P; Granule Membrane Protein 140kDa; Granule Membrane Protein 140; P Selectin; GMP 140; LECAM3; Selectin P Granule Membrane Protein 140kD; Antigen CD62 Platelet Alpha-Granule Membrane Protein; Granulocyte Membrane Protein; CD62P Antigen; Antigen CD62; GMRP |
Application Instructions
| Application Suggestion |
|
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SELP |
| Gene Full Name | Selectin P |
| Background | This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. |
| Function | Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. [UniProt] |
| Cellular Localization | Cell membrane |
| Calculated MW | ~ 140 kDa |
| PTM | Disulfide bond, Glycoprotein, Lipoprotein, Palmitate |
Images (2) Click the Picture to Zoom In
-
ARG43816 anti-CD62P / P-Selectin antibody WB image
Western blot: Mouse heart and Rat heart cell tissue stained with ARG43816 anti-CD62P / P-Selectin antibody at 1:1000 dilution.
-
ARG43816 anti-CD62P / P-Selectin antibody FACS image
Flow Cytometry: RAW264.7 cells stained with ARG43816 anti-CD62P / P-Selectin antibody at1 :50 dilution.
