ARG20959
anti-CD62E / E-Selectin antibody [1.2B6] (PE)
anti-CD62E / E-Selectin antibody [1.2B6] (PE) for Blocking,ELISA,Flow cytometry,ICC/IF,IHC-Frozen sections,Western blot and Human,Pig
Overview
| Product Description | PE-conjugated Mouse Monoclonal antibody [1.2B6] recognizes CD62E / E-Selectin |
|---|---|
| Tested Reactivity | Hu, Pig |
| Tested Application | BL, ELISA, FACS, ICC/IF, IHC-Fr, WB |
| Specificity | Human CD62E & CD62P/Porcine CD62E. The clone 1.2B6 recognizes a common epitope shared by CD62E and CD62P. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1.2B6 |
| Isotype | IgG1, kappa |
| Target Name | CD62E / E-Selectin |
| Antigen Species | Human |
| Immunogen | TNF stimulated human endothelial cells |
| Conjugation | PE |
| Alternate Names | E-selectin; CD62E; ELAM-1; ELAM1; CD antigen CD62E; ELAM; Endothelial leukocyte adhesion molecule 1; Leukocyte-endothelial cell adhesion molecule 2; ESEL; LECAM2; CD62 antigen-like family member E |
Application Instructions
| Application Suggestion |
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| Application Note | WB: Under non-reducing condition. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS, 0.1% Sodium azide and Sucrose. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | Sucrose |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SELE |
| Gene Full Name | selectin E |
| Background | The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008] |
| Function | Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis. [UniProt] |
| Calculated MW | 67 kDa |
Images (1) Click the Picture to Zoom In
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ARG20959 anti-CD62E / E-Selectin antibody [1.2B6] (PE) FACS image
Flow Cytometry: PMA and lonomycin-stimulated human endothelial cell line HUV-EC-C stained with ARG20959 anti-CD62E / E-Selectin antibody [1.2B6] (PE).
