ARG45056
anti-CD321 / JAM1 antibody
anti-CD321 / JAM1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit polyclonal antibody recognizes CD321 / JAM1. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD321 / JAM1 |
| Antigen Species | Human |
| Immunogen | Human JAM-A/F11R recombinant protein (a.a: S28-T294). |
| Conjugation | Un-conjugated |
| Alternate Names | F11R; F11 Receptor; PAM-1; JCAM; Junctional Adhesion Molecule 1; JAM-1; JAM-A; CD321; JAMA; JAM1; Junctional Adhesion Molecule A; Platelet Adhesion Molecule 1; Platelet F11 Receptor; CD321 Antigen; JAM; KAT |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | F11R |
| Gene Full Name | F11 receptor |
| Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008] |
| Function | Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. [UniProt] |
| Calculated MW | 33 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt] |
Images (4) Click the Picture to Zoom In
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ARG45056 anti-CD321 / JAM1 antibody IHC-P image
Immunohistochemistry: Human colonic adenocarcinoma stained with ARG45056 anti-CD321 / JAM1 antibody at 2 μg/ml dilution.
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ARG45056 anti-CD321 / JAM1 antibody ICC/IF image
Immunofluorescence: T-47D stained with ARG45056 anti-CD321 / JAM1 antibody at 5 μg/ml dilution.
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ARG45056 anti-CD321 / JAM1 antibody WB image
Western blot: T-47D, A431 and RT4 stained with ARG45056 anti-CD321 / JAM1 antibody at 0.5 μg/ml dilution.
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ARG45056 anti-CD321 / JAM1 antibody FACS image
Flow Cytometry: Daudi stained with ARG45056 anti-CD321 / JAM1 antibody at 1 μg/1x10^6 cells dilution.
