ARG56012
anti-CD32 antibody [7.3]
anti-CD32 antibody [7.3] for ICC/IF and Human
Overview
| Product Description | Mouse Monoclonal antibody [ 7.3 ] recognizes CD32 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 7.3 |
| Isotype | IgG1, kappa |
| Target Name | CD32 |
| Antigen Species | Human |
| Immunogen | K562 and FcgRII+L cells. |
| Conjugation | Un-conjugated |
| Alternate Names | Fc-gamma RII-a; CD antigen CD32; FcGR; IgG Fc receptor II-a; FCGR2A1; CD32A; FCGR2; Low affinity immunoglobulin gamma Fc region receptor II-a; FcRII-a; Fc-gamma-RIIa; FCG2; IGFR2; CD32; CDw32 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 0.1 mg/ml BSA |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P12318 Human Low affinity immunoglobulin gamma Fc region receptor II-a |
|---|---|
| Gene Symbol | FCGR2A |
| Gene Full Name | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| Background | This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008] |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. [UniProt] |
| Cellular Localization | Cell surface |
| Calculated MW | 35 kDa |
| PTM | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
