ARG65188
anti-CD305 / LAIR1 antibody
anti-CD305 / LAIR1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Immune System antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes CD305 / LAIR1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Specificity | This antibody is expected to recognize both isoforms (NP_002278.1; NP_068352.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD305 / LAIR1 |
| Antigen Species | Human |
| Immunogen | C-NDTEDVSQASPSE |
| Conjugation | Un-conjugated |
| Alternate Names | LAIR-1; hLAIR1; CD305; CD antigen CD305; Leukocyte-associated immunoglobulin-like receptor 1 |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6GTX8 Human Leukocyte-associated immunoglobulin-like receptor 1 |
|---|---|
| Background | The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. [provided by RefSeq, Jul 2008] |
| Research Area | Immune System antibody |
| Calculated MW | 31 kDa |
| PTM | Phosphorylation at Tyr-251 and Tyr-281 activates it. May be phosphorylated by LCK. N-glycosylated. |
Images (2) Click the Picture to Zoom In
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ARG65188 anti-CD305 / LAIR1 antibody WB image
Western blot: Human Lymph Node lysate (35 µg protein in RIPA buffer) stained with ARG65188 anti-CD305 / LAIR1 antibody at 2 µg/ml dilution.
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ARG65188 anti-CD305 / LAIR1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human tonsil tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG65188 anti-CD305 / LAIR1 antibody at 3.75 µg/ml dilution followed by AP-staining.
