ARG63771

anti-CD2BP2 antibody

anti-CD2BP2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes CD2BP2
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CD2BP2
Antigen Species Human
Immunogen PKRKVTFQGVGDE-C
Conjugation Un-conjugated
Alternate Names CD2 tail-binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; PPP1R59; LIN1; U5-52K; FWP010; U5 snRNP 52K protein; Snu40; CD2 cytoplasmic domain-binding protein 2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P5 - 10 µg/ml
WB0.3 - 1.0 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10421 Human CD2BP2

Swiss-port # O95400 Human CD2 antigen cytoplasmic tail-binding protein 2

Background This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]
Research Area Immune System antibody
Calculated MW 38 kDa

Images (2) Click the Picture to Zoom In

  • ARG63771 anti-CD2BP2 antibody WB image

    Western Blot: Human Thymus lysate (35 µg protein in RIPA buffer) stained with ARG63771 anti-CD2BP2 antibody at 0.3 µg/ml dilution.

  • ARG63771 anti-CD2BP2 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Spleen. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63771 anti-CD2BP2 antibody at 5 µg/ml dilution followed by AP-staining.