ARG21185

anti-CD28 antibody [AV7] (PE)

anti-CD28 antibody [AV7] (PE) for Flow cytometry,ICC/IF,IHC-Frozen sections and Chicken,Turkey

Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody

Overview

Product Description PE-conjugated Mouse Monoclonal antibody [AV7] recognizes CD28
Tested Reactivity Chk, Turkey
Tested Application FACS, ICC/IF, IHC-Fr
Specificity Chicken/Turkey CD28. The clone AV7 also reacts with turkey CD28 as demonstrated by flow cytometry.
Host Mouse
Clonality Monoclonal
Clone AV7
Isotype IgG1, kappa
Target Name CD28
Antigen Species Chicken
Immunogen Chicken peripheral blood lymphocytes
Conjugation PE
Alternate Names Tp44; TP44; T-cell-specific surface glycoprotein CD28; CD antigen CD28

Application Instructions

Application Suggestion
Tested Application Dilution
FACS< 0.2 µg/10^6 cells
ICC/IFAssay-dependent
IHC-FrAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS, 0.1% Sodium azide and Sucrose.
Preservative 0.1% Sodium azide
Stabilizer Sucrose
Concentration 0.1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 396249 Chicken CD28

Swiss-port # P31043 Chicken T-cell-specific surface glycoprotein CD28 homolog

Gene Symbol CD28
Gene Full Name CD28 molecule
Background The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
Function Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. [UniProt]
Research Area Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody
Calculated MW 25 kDa
PTM CD40LG induces tyrosine phosphorylation of isoform 3.

Images (1) Click the Picture to Zoom In

  • ARG21185 anti-CD28 antibody [AV7] (PE) FACS image

    Flow Cytometry: Chicken peripheral blood mononuclear cells stained with ARG21185 anti-CD28 antibody [AV7] (PE) and ARG21151 anti-CD3 epsilon antibody [CT-3] (FITC).