ARG21183
anti-CD28 antibody [AV7] (FITC)
anti-CD28 antibody [AV7] (FITC) for Flow cytometry,ICC/IF,IHC-Frozen sections and Chicken,Turkey
Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody
Overview
| Product Description | FITC-conjugated Mouse Monoclonal antibody [AV7] recognizes CD28 |
|---|---|
| Tested Reactivity | Chk, Turkey |
| Tested Application | FACS, ICC/IF, IHC-Fr |
| Specificity | Chicken/Turkey CD28. The clone AV7 also reacts with turkey CD28 as demonstrated by flow cytometry. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | AV7 |
| Isotype | IgG1, kappa |
| Target Name | CD28 |
| Antigen Species | Chicken |
| Immunogen | Chicken peripheral blood lymphocytes |
| Conjugation | FITC |
| Alternate Names | Tp44; TP44; T-cell-specific surface glycoprotein CD28; CD antigen CD28 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 0.1% Sodium azide. |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.5 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P31043 Chicken T-cell-specific surface glycoprotein CD28 homolog |
|---|---|
| Gene Symbol | CD28 |
| Gene Full Name | CD28 molecule |
| Background | The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] |
| Function | Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. [UniProt] |
| Research Area | Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody |
| Calculated MW | 25 kDa |
| PTM | CD40LG induces tyrosine phosphorylation of isoform 3. |
Images (1) Click the Picture to Zoom In
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ARG21183 anti-CD28 antibody [AV7] (FITC) FACS image
Flow Cytometry: Chicken peripheral blood lymphocytes stained with ARG21183 anti-CD28 antibody [AV7] (FITC) and ARG21153 anti-CD3 antibody [CT-3] (PE).
