ARG22009

anti-CD28 antibody [37.51] (Biotin)

anti-CD28 antibody [37.51] (Biotin) for Blocking,Cellular activation ,Flow cytometry and Mouse

Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody

Overview

Product Description Biotin-conjugated Syrian Hamster Monoclonal antibody [37.51] recognizes CD28
Tested Reactivity Ms
Tested Application BL, Cell-Act , FACS
Specificity Mouse CD28
Host Hamster
Clonality Monoclonal
Clone 37.51
Isotype IgG2
Target Name CD28
Antigen Species Mouse
Immunogen C57BL/6N Mouse T cell lymphoma EL-4 cell line
Conjugation Biotin
Alternate Names Tp44; TP44; T-cell-specific surface glycoprotein CD28; CD antigen CD28

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
Cell-Act Assay-dependent
FACS< 2 µg/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS and 0.1% Sodium azide.
Preservative 0.1% Sodium azide
Concentration 0.5 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12487 Mouse CD28

Swiss-port # P31041 Mouse T-cell-specific surface glycoprotein CD28

Gene Symbol CD28
Gene Full Name CD28 antigen
Background The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
Function Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. [UniProt]
Research Area Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody
Calculated MW 25 kDa
PTM CD40LG induces tyrosine phosphorylation of isoform 3.

Images (1) Click the Picture to Zoom In

  • ARG22009 anti-CD28 antibody [37.51] (Biotin) FACS image

    Flow Cytometry: BALB/c Mouse thymocytes stained with ARG22009 anti-CD28 antibody [37.51] (Biotin) and ARG20819 anti-CD3e antibody [C363.29B] (PE).