ARG55418
anti-CD272 / BTLA antibody
anti-CD272 / BTLA antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Immune System antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD272 / BTLA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Specificity | BTLA antibody is human specific. At least two isoforms of BTLA are known to exist. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD272 / BTLA |
| Antigen Species | Human |
| Immunogen | Synthetic peptide (17 aa) within aa. 170-220 of Human BTLA. |
| Conjugation | Un-conjugated |
| Alternate Names | CD antigen CD272; BTLA1; B- and T-lymphocyte-associated protein; B- and T-lymphocyte attenuator; CD272 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Cat. No. 1205- Jurkat Cell Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BTLA |
| Gene Full Name | B and T lymphocyte associated |
| Background | This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011] |
| Function | Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. [UniProt] |
| Research Area | Immune System antibody |
| Calculated MW | 33 kDa |
| PTM | Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11. N-glycosylated. |
Images (3) Click the Picture to Zoom In
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ARG55418 anti-CD272 / BTLA antibody WB image
Western blot: Jurkat cell lysate at (A) 1 and (B) 2 µg/ml stained with ARG55418 anti-CD272 / BTLA antibody at (A) 1 and (B) 2 µg/ml dilution.
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ARG55418 anti-CD272 / BTLA antibody IHC image
Immunohistochemistry: Human small intestine tissue stained with ARG55418 anti-CD272 / BTLA antibody at 20 µg/ml dilution.
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ARG55418 anti-CD272 / BTLA antibody IHC image
Immunohistochemistry: Human small intestine tissue stained with ARG55418 anti-CD272 / BTLA antibody at 2.5 µg/ml dilution.
