ARG42584

anti-CD268 / BAFF R antibody

anti-CD268 / BAFF R antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CD268 / BAFF R
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CD268 / BAFF R
Antigen Species Human
Immunogen Recombinant protein corresponding to M1-L78 of Human CD268 / BAFF R.
Conjugation Un-conjugated
Alternate Names CD antigen CD268; BROMIX; BAFF-R; CD268; Tumor necrosis factor receptor superfamily member 13C; BAFF receptor; BAFFR; B-cell-activating factor receptor; prolixin; CVID4; BLyS receptor 3

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 19 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose.
Preservative 0.05% Sodium azide
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 115650 Human TNFRSF13C

GeneID: 72049 Mouse TNFRSF13C

Swiss-port # Q96RJ3 Human Tumor necrosis factor receptor superfamily member 13C

Swiss-port # Q9D8D0 Mouse Tumor necrosis factor receptor superfamily member 13C

Gene Symbol TNFRSF13C
Gene Full Name tumor necrosis factor receptor superfamily, member 13C
Background B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
Function B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. [UniProt]
Cellular Localization Membrane; Single-pass type III membrane protein. [UniProt]
Calculated MW 19 kDa

Images (1) Click the Picture to Zoom In

  • ARG42584 anti-CD268 / BAFF R antibody WB image

    Western blot: 50 µg of samples under reducing conditions. Jurkat, Rat spleen, Rat thymus, Mouse spleen and Mouse thymus lysates stained with ARG42584 anti-CD268 / BAFF R antibody at 0.5 µg/ml dilution, overnight at 4°C.