ARG43897
anti-CD262 / TRAIL R2 antibody
anti-CD262 / TRAIL R2 antibody for ELISA,Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD262 / TRAIL R2 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | ELISA, FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | CD262 / TRAIL R2 |
| Antigen Species | Human |
| Immunogen | Human CD262 / TRAIL R2 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Tumor necrosis factor receptor superfamily member 10B |
| Alternate Names | TNFRSF10B; TNF Receptor Superfamily Member 10b; TRAIL-R2; TRAILR2; KILLER; DR5; TRICK2A; TRICKB; CD262; Tumor Necrosis Factor Receptor Superfamily, Member 10b; Tumor Necrosis Factor Receptor Superfamily Member 10B; TNF-Related Apoptosis-Inducing Ligand Receptor 2; Death Receptor 5; TRICK2; ZTNFR9; P53-Regulated DNA Damage-Inducible Cell Death Receptor(Killer); Tumor Necrosis Factor Receptor-Like Protein ZTNFR9; Death Domain Containing Receptor For TRAIL/Apo-2L; Apoptosis Inducing Protein TRICK2A/2B; Apoptosis Inducing Receptor TRAIL-R2; Cytotoxic TRAIL Receptor-2; Fas-Like Protein; TRAIL Receptor 2; CD262 Antigen; KILLER/DR5; TRICK2B |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # O14763 Human Tumor necrosis factor receptor superfamily member 10B |
|---|---|
| Gene Symbol | TNFRSF10B |
| Gene Full Name | TNF Receptor Superfamily Member 10b |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
| Function | Receptor for the cytotoxic ligand TNFSF10/TRAIL |
| Cellular Localization | Membrane |
| Calculated MW | 48 kDa |
| PTM | Disulfide bond, Glycoprotein |
Images (5) Click the Picture to Zoom In
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ARG43897 anti-CD262 / TRAIL R2 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG43897 anti-CD262 / TRAIL R2 antibody at 2 μg/ml dilution.
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ARG43897 anti-CD262 / TRAIL R2 antibody WB image
Western blot: K562 with ARG43897 anti-CD262 / TRAIL R2 antibody at 0.5 μg/mL dilution.
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ARG43897 anti-CD262 / TRAIL R2 antibody FACS image
Flow Cytometry: 293T cells stained with ARG43897 anti-CD262 / TRAIL R2 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43897 anti-CD262 / TRAIL R2 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG43897 anti-CD262 / TRAIL R2 antibody at 2 μg/ml dilution.
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ARG43897 anti-CD262 / TRAIL R2 antibody WB image
Western blot: PC-12 with ARG43897 anti-CD262 / TRAIL R2 antibody at 0.5 μg/mL dilution.
