ARG23889

anti-CD23 antibody [Tu1]

anti-CD23 antibody [Tu1] for Blocking,Flow cytometry,ICC/IF,IHC-Frozen sections,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [Tü1] recognizes CD23
Tested Reactivity Hu
Tested Application BL, FACS, ICC/IF, IHC-Fr, WB
Host Mouse
Clonality Monoclonal
Clone Tü1
Isotype IgG3, kappa
Target Name CD23
Antigen Species Human
Immunogen Purified Human tonsil lymphocytes (KR3598 cells).
Conjugation Un-conjugated
Alternate Names CD23A; BLAST-2; Lymphocyte IgE receptor; CLEC4J; Immunoglobulin E-binding factor; CD23; IGEBF; Fc-epsilon-RII; CD antigen CD23; FCE2; Low affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4 member J

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
FACS< 1 µg/10^6 cells
ICC/IFAssay-dependent
IHC-FrAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer BBS (pH 8.2)
Concentration 0.1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2208 Human FCER2

Swiss-port # P06734 Human Low affinity immunoglobulin epsilon Fc receptor

Gene Symbol FCER2
Gene Full Name Fc fragment of IgE, low affinity II, receptor for (CD23)
Background The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [UniProt]
Cellular Localization Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23. [UniProt]
Calculated MW 36 kDa
PTM N- and O-glycosylated.

The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG23889 anti-CD23 antibody [Tü1] FACS image

    Flow Cytometry: Human peripheral blood lymphocytes stained with ARG23889 anti-CD23 antibody [Tü1] and anti-Human CD3 antibody (PE) followed by ARG21899 Goat anti-Mouse IgG3 antibody (FITC), pre-adsorbed.