ARG42361
anti-CD21 antibody [LT21] (PerCP)
anti-CD21 antibody [LT21] (PerCP) for Flow cytometry and Human,Cow,Dog,Pig
Overview
| Product Description | PerCP-conjugated Mouse Monoclonal antibody [LT21] recognizes CD21 |
|---|---|
| Tested Reactivity | Hu, Cow, Dog, Pig |
| Tested Application | FACS |
| Specificity | The antibody LT21 reacts with an extracellular epitope of CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | LT21 |
| Isotype | IgG1 |
| Target Name | CD21 |
| Antigen Species | Human |
| Immunogen | IM9 Human B-lymphoblastoid cell line. |
| Conjugation | PerCP |
| Alternate Names | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified |
| Buffer | PBS and 15 mM Sodium azide. |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CR2 |
| Gene Full Name | complement component (3d/Epstein Barr virus) receptor 2 |
| Background | This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| Function | Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047). (Microbial infection) Acts as a receptor for Epstein-Barr virus. [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 113 kDa |
Images (2) Click the Picture to Zoom In
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ARG42361 anti-CD21 antibody [LT21] (PerCP) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG42361 anti-CD21 antibody [LT21] (PerCP) at 10 µl / 100 µl of peripheral whole blood.
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ARG42361 anti-CD21 antibody [LT21] (PerCP) FACS image
Flow Cytometry: Separation of Human CD21 lymphocytes (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG42361 anti-CD21 antibody [LT21] (PerCP) at 10 µl / 100 µl of peripheral whole blood.
